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MEDICAL
AromaJet.com is developing a new technology for identifying dementing brain disorders, including Alzheimer’s, Huntington’s, and Parkinson’s and for differentiating them from other mental disorders. This method is based on detecting the olfactory deficits that are diagnostic of the dementing disease.

AromaJet.com’s digital Olfactometer is based on current microjetting technology. It utilizes a microdispenser, which contains an odorant volume dispenser, resolution of 200 pL. Each dispensing channel is digitally and instantaneously (<10ms cycle time) addressable.
This system will allow exploration of entirely new dimensions in the area of human olfaction. By presenting brief clouds of odoriferous vapor, the temporal integration (~100ms) of sensory responsiveness of the olfactory mucosa can be examined.

The complete system for multiple fluid testing is pictured. The control box contains a microprocessor, LCD display, and operator buttons and has the capacity to download test data. The controller is preprogrammed to step the drop count by logarithmic increments and insure adequate recovery time for the subject between trials.

Dr. R. M. Stewart of Presbyterian Hospital of Dallas will present a paper at the Experimental Biology 2000 Conference in April. The olfactometer was used to quantify the olfactory deficits in sensory systems in Alzheimer and Parkinson patients. The new digital instrument offers quantitative assessment of olfactory threshold in the clinical setting and may be used for early detection of neurodegenerative disorders. The digital aroma generating technology was invented by MicroFab Technologies in the mid-nineties.